EVIDENCE BASED CARE

QoL

In EVIDILYA, Quality-of-Life (QoL) insurance and improvement are key elements to be pursued through research. Methodologies involving the use of quality-of-life patient outcomes in observational and interventional health studies are based on extensive and diverse research methods.

A wide range of Quality-of-Life parameters are constantly updated to stay abreast of new trends and actual needs in the field of human health.

Our mission is:

• to provide professional assistance using our database of academic and professional researchers interested in QoL studies, with the aim of combining efforts and interests to enhance the field of QoL studies in different research areas;
• to interact with academic institutions (organizations, university hospitals, international associations, etc.) in scientific areas related to: product areas, clinical trial designs and full services appraisals of the QoL of general populations and specific groups (such as segments of diverse age group, neighborhoods, nations, etc.);
• to promote better cooperation between stakeholders involved in QoL studies by developing superior QoL methodologies for various segment groups and improving the quality of intervention strategies and plans;
• to encourage cooperation with other organizations regarding QoL studies in order to create a group of international QoL researchers worldwide.

EVIDENCE BASED CARE

Real life evaluation

Real life evaluation provides opportunities to discover new products, to prioritize asset development, to support decision-making and deliver more efficient and insightful assessment. Real life evaluation provides a new and unique commercial model that delivers mutually beneficial partnerships between companies and the health system.

EVIDILYA can extract relevant real-world data from existing health information sources an can analyze them to provide research solutions that take into account the key factors influencing outcomes.

We can collect data that demonstrates real world product value, safety and effectiveness and generates scientific evidence.

Discover how real-world evidence can create opportunities at different stages of the product development process:

R&D stage

• Identify unmet need through disease and treatment understanding and epidemiology exploration;
• Explore causes and stratify disease and understand patient behaviour;
• Support R&D managing in decision making process and improve stakeholder collaboration.

Clinical trial stage

• Boost cohort enrolment through a recruitment process support and target population selection;
• Manage trial design based on new sources of data collection.

Commercial stage

• Explore BD opportunities;
• Analyze and track economic value;
• Provide estimates for inputs used in health economic evaluations.

In EVIDILYA we select and personalize the methods that underpin better understanding of worldwide people needs and satisfaction. Preferences and individuals’ habits keep changing; therefore, companies are required to re-evaluate their products and processes in order to meet the requirements of an increasingly demanding client.

The analysis of trends, hidden needs and consumer choices provides important information to aid with the definition, development or re-design of a product, package or concept.

We have developed strategic solutions to have the opportunity to adopt a pre-market and post-market based analysis to assess what consumers think about their product at various stages of development. These solutions include:

U&A (USAGE&ATTITUDES)

PURCHASE FUNNEL HABITS

PATIENT EXPERIENCE JOURNEY

PRODUCT/COMMUNICATION TEST

SENSITIVE TEST

USABILITY TEST

EVIDENCE BASED CARE

Prospective/retrospective/ambispective studies

When considering the classification of Real-World Evidence (RWE) studies, it is essential to understand the three distinct designs: prospective, retrospective, and ambispective.

In a Prospective RWE study, data is gathered in real-time, following patients longitudinally, and allowing the evaluation of interventions under real-world conditions. This setting provides valuable insights into effectiveness and safety profiles and is useful for assessing treatment outcomes over time.

Retrospective RWE studies, in contrast, use existing data from various sources like electronic health records or claims databases to evaluate treatment patterns, outcomes, and potential associations. Analyzing data retrospectively enables researchers to conduct cost-effective assessments of treatment effectiveness, comparative effectiveness, and safety outcomes. This design is especially helpful when conducting population-based research. . While they can be quicker and often less expensive than prospective studies, they may be limited by the availability and quality of existing data.

The Ambispective setting is a mixture of prospective and retrospective designs, where new data is collected while incorporating pre-existing data sources. For example, a study might start by looking at existing data on blood pressure medication effectiveness, and then continue to collect future data on new patients taking the medication This approach offers a more nuanced analysis of real-world treatment patterns, outcomes, and adverse events, providing a comprehensive view of patient health while maintaining the efficiency of retrospective collection methods.

Each setting provides unique insights into patient outcomes and offers advantages that are useful in different clinical research scenarios.

Evidilya possesses extensive expertise in various RWE settings, showcasing a comprehensive understanding of the diverse healthcare and research environments. With a highly agile and flexible approach, Evidilya adapts to the unique requirements of configuration, offering tailored solutions that meet the specific needs and objectives of clients. This adaptable approach allows Evidilya to effectively navigate the complexities of real-world data collection, analysis, and interpretation, ensuring reliable and meaningful insights for evidence-based decision-making in healthcare and research.

HEALTH TRENDS AND ECONOMICS

Burden of disease impact study

The increase in disease and disease-related consequences can significantly affect society: determining the behaviour of people, the structure of the health system and the decisions of the regulatory authorities. Hence there is a need for studies based on tangible, reliable and high-quality evidence.

Burden of disease is a modelling technique that combines multiple data sources to count and compare the total number of people affected by certain diseases and injuries in a population (accounting for fatal and non-fatal incidence). This method also relates disease burden to specific risk factors:

Incidence and prevalence analysis

Epidemiological indices like prevalence and incidence are frequently used as an epidemiological measure to assess how commonly a disease or a condition occurs in a population. These values provide the required data to quantify the impact of a pathological condition and related risk factors.

By establishing partnerships with strategic key opinion leaders and disease experts, we are able to access, collect and process data in order to conduct descriptive epidemiology studies and estimate disease prevalence and incidence.

With this information we aim to achieve the following key objectives:

• understand health parameters and disease frequency and distribution;
• understand health related events such as diseases, causes of death and risk factors description;
• understand comparisons between the age groups, and between populations;
• provide tools to be used at the global, national and local level to anticipate health trends.

Health economics studies

Health economics promote health through the study of healthcare providers, hospitals and clinics, managed care and public health promotion activities. Health economists apply the theories of production, efficiency, disparity, competition and regulation to provide the public and private sector with extensive information about the most efficient, cost-effective and equitable action.

These studies can promote policy that enhances economic and social well-being. They can also influence health industry decision making process and consumer choices. Furthermore, value, budget impact and cost effectiveness are crucial considerations for formulary acceptance and market access of the product.

EVIDILYA conducts research programmes in the field of health economics to estimate some of the main health economic indices:

• Cost-Effectiveness Analysis, CEA
• Cost-Minimization Analysis, CMA
• Cost-Utility Analysis, CUA
• Cost-Benefit Analysis, CBA

Disease economic and cost analysis data

We offer consultancy service to explore direct and indirect costs associated with a specific disease, providing strategic information on the cost/benefit ratio through data collection and analysis:

• pharma-epidemiology analysis;
• pharma-economic analysis;
• cost of illness;
• health technology assessment;
• educational projects.

HEALTH TRENDS AND ECONOMICS

Product economic analysis

The introduction of a new product on the market requires a full economic assessment by the competent authorities. Said evaluation should explain the product’s economic impact on the health system. High-quality scientific services are required to meet the growing demand of health authorities and support convincing evidence to substantiate the value of a product.

EVIDILYA is committed in client strategy support, optimizing the decision pricing strategy on product ensuring market access in many countries.

We are able to offer a 360° support approach to define recommendations for the introductory price of a product, through the implementation of targeted survey to identify:

• economic impact studies;
• market and competitors analysis;
• consumer opinion collection and ideal price identification in respect of expectations of costs.

HEALTHCARE PROFESSIONAL ATTITUDES

Health interview survey

Understanding the attitudes and behaviours of key influencers may be a strategic way to anticipate trends related to the opinions of healthcare professionals. EVIDILYA can conduct specific surveys directly addressed to healthcare professionals in order to identify and analyze their opinions, providing an overview of medical practices and patient recommendations related to our customers’ products.

HEALTHCARE PROFESSIONAL ATTITUDES

KoL services

Key Opinion Leaders (KOLs) are specialists in their chosen field. Their opinions are held in high regard by both their peers and the public at large. Key opinion leaders play an important role in marketing strategy at every stage of the product lifecycle.

EVIDILYA are experienced in KOL mapping and identification globally, nationally, regionally and locally. Connecting with these opinion leaders helps with designing a powerful and innovative research programme that predicts how a market will be shaped in the future. The contribution of KOLs can also help you develop products that meet the exact needs of your target customers.